The Current Oral Protocol

The current Niacin Restoration Protocol includes Flush Niacin and L-glutamine in a ratio of 1 measure of Niacin to 1.2 measure of L-Glutamine. For example, if you were at the dose of 1 gram of Niacin, you would add 1.2 grams of L-Glutamine. The basis of all current protocols that we follow comes from here. The basic protocol may change so check back frequently here. For previous protocols, go here.

Dosing & Progression Guidelines for Adults

Below is the therapeutic progression we have been using. This is just a guideline. If you decide to try this protocol, do it at your own pace. The starting dose for the majority of people is 500 mg of Niacin to begin. You will definitely feel a flush the first time. Do not be alarmed. For information about the Flush and what to expect, go here. Once we no longer felt the flush, we started bumping up the Niacin by 500 mg and the corresponding dose of L-glutamine. Some people go low and slow. Others (like biohackers) progress very quickly. Listen to your body. We started with capsules and as we progressed, we switched to buying in bulk as it is easier and less expensive. For seriously ill people or for those who have a long history of alcohol, drug or pharmaceutical use, you may need to start as low as 100 mg of Niacin and work your way up. You can also do these low doses up to 3 times daily, if necessary. Once you review the protocol, go here to buy products.

According to experts, deep healing does not occur until you reach therapeutic levels of Flush Niacin (2-5 grams and some even go as high as 10 grams for serious or chronic conditions). Most people do this protocol once a day and some bump up to twice a day. Again, listen to your body.

Note: If you are under a doctor’s care and/or are currently on a lot of prescription pharmaceuticals, please consult with your medical provider before embarking on this protocol.

Special Note: Most people take protocol 20-30 minutes after a meal.

GuidlinesNiacin Dose L-Glutamine Dose
Starting dose for seriously ill people or substance users. Bump up to twice a day to see how that feels. Then start bumping up 100 mg at a time, if that feels right. 100 mg120 mg
Starting dose for most people. Slowly bump up to next dose in 500 mg increments. If you have too strong a reaction or concerning side effects, bump back down. Listen to your body.500 mg600 mg
Next dose increase. If you have too strong a reaction or concerning side effects, bump back down. Listen to your body.1 gram
(1,000 mg)
1.2 grams (1,200 mg)
Next dose increase. If you have too strong a reaction or concerning side effects, bump back down. Listen to your body.1.5 grams
(1,500 mg)
1.8 grams (1,800 mg)
Start of therapeutic doses. If you have too strong a reaction or concerning side effects, bump back down. Listen to your body.2 grams
(2,000 mg)
2.4 grams (2,400 mg)
Next therapeutic dose increase. If you have too strong a reaction or concerning side effects, bump back down. Listen to your body.2.5 grams
(2,500 mg)
3 grams (3,000 mg)
Next therapeutic dose increase. If you have too strong a reaction or concerning side effects, bump back down. Listen to your body.3 grams
(3,000 mg)
3.6 grams (3,600 mg)
Next therapeutic dose increase. If you have too strong a reaction or concerning side effects, bump back down. Listen to your body.3.5 grams
(3,500 mg)
4.2 grams (4,200 mg)
Next therapeutic dose increase. If you have too strong a reaction or concerning side effects, bump back down. Listen to your body.4 grams
(4,000 mg)
4.8 grams (4,800 mg)
Next therapeutic dose increase. If you have too strong a reaction or concerning side effects, bump back down. Listen to your body.4.5 grams
(3,500 mg)
5.4 grams (5,400 mg)
Next therapeutic dose increase. If you have too strong a reaction or concerning side effects, bump back down. Listen to your body.5 grams
(4,000 mg)
6 grams (6,000 mg)
Consult an expert for anything over 5 gramsOver 5 gramsConsult our

Our Add-Ons to the Protocol

Two things that our team has added to our protocol is:

  • Raw milk – some people find it very beneficial to mix the protocol in raw milk (cold, as l-glutamine loses its effectiveness in warm liquid). Raw milk has so many benefits and the protocol mixes so well with Not everyone has access to raw milk. Trying finding a source in the US here or worldwide here.
  • Zeolitezeolite is an amazing detox product that helps bind toxins and heavy metals and effectively carry them out of our body. We have found it to be very helpful taking it about 20-30 minutes after taking your Niacin protocol. We prefer Touchstone Essentials zeolite Pure Body Extra Spray and/or Fulvic Minerals+ products. Most people do the spray 3 times a day OR the spray 2 times a day + Fulvic Minerals+ once a day.


Tips for Success

  • Timing – We usually take protocol 20-30 minutes after a meal. If you take on an empty stomach, the flush may be much stronger.
  • Capsules vs Bulk – Some people start the protocol with capsules to test it out. If you proceed further, we recommend switching to the bulk forms of each item once you run out of capsules as it is easier to measure and much cheaper. Take a look at our buying guide to see what works for you.
  • Mix with Water (Cold or Room Temperature) – Take protocol with pure filtered water or distilled water. If you are taking items in bulk, be sure to mix them in a 6-10 oz glass of water. Mix well and let it sit a couple of minutes so its all dissolved. Then drink all at once. Your flush should start shortly. If you are using capsules, you can even empty the capsules into water and mix well. Do NOT use warm water with this protocol as it will destroy L-Glutamine. Warm water is fine with the other protocols that did not include L-Glutamine.
  • Pharmaceuticals – It is recommended by doctors who use this protocol to avoid ALL pharmaceuticals, even over the counter ones, during this protocol, if possible. If you are on a lot of prescription pharmaceuticals or under a doctor’s care, consult with your medical provider before embarking on this protocol. We do not recommend getting off any life-saving medication. Please consult your doctor.
  • Other Supplements– We recommend not taking any other supplements during this protocol to best observe the full therapeutic benefits. In our research we discovered that once your Niacin levels are restored, you will not need to supplement with things like Vitamin C, Vitamin D, Zinc, etc. anymore as they will be restored as well. Note: we did however continue to use the Zeolite Pure Body Extra detox spray as we felt it would not impede Niacin uptake and would further help your body to gently detox.
  • Phenols – Avoid coffee, tea, and alcohol as they can hinder the restoration of your Niacin levels due to high levels of phenols. If you must have coffee, we advise that you make sure you drink it a few hours away from taking your Niacin protocol. Alcohol will negatively affect the benefit of the flush.
  • Therapeutic doses – If you need to heal deep or chronic health issues, consider progressing up to the therapeutic doses (2g – 5g Niacin for Adults). If you do not have deep issues to heal, consider staying at the maintenance/prophylactic dose.
  • Side Effects – As you progress, you may feel unpleasant side effects from the flush such as a racing heart rate, a lot of mucus coming up, cough or scratchy throat, etc. That is your body detoxing. If these effects concern you, try bumping your dose back down and taking it slower. Listen to your body. Take this at your own pace. Consult a coach if you need to.

Dietary Tips

The following are dietary tips for when you are on the protocol:

  • Water – drink as much pure, filtered or distilled water as you can. 
  • Avoid coffee, tea or alcohol. They interfere with the protocol. If you must drink coffee or tea, make sure it is hours away from the Niacin protocol.
  • Food – eat a balanced diet. Try to include all food groups (meat, fish, dairy, fruit, veggies, grains). It would not be advisable to fast during the protocol.
  • Raw Milk – if you have access to raw milk, it is very beneficial while on the protocol. Trying finding a source in the US here or worldwide here.

Children’s Protocol Guidelines


May the Flush Be With You!





***Disclaimer: This website was created for informational purposes only and has no ties to any supplement or drug company or any doctor. The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website. We are merely biohackers, trying to heal ourselves and passing our knowledge, research and experience onto others.***